| 不同大小甲状腺乳头状癌实时超声造影特征与颈部淋巴结转移的关系 |
| 投稿时间：2016-12-08 修订日期：2017-01-11 点此下载全文 |
| 引用本文：周易,梁蕾,郭君.不同大小甲状腺乳头状癌实时超声造影特征与颈部淋巴结转移的关系[J].医学研究杂志,2017,46(9):157-160,167 |
| DOI：
10.11969/j.issn.1673-548X.2017.09.040 |
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| 中文摘要:目的 分析不同大小甲状腺乳头状癌（PTC）实时超声造影（CEUS）特征与颈部淋巴结转移的关系。方法 98例甲状腺可疑结节患者进行常规超声及超声造影检查，对52例经手术病理证实为甲状腺乳头状癌结节进行超声造影特征的分析，并分别对结节周边与中心感兴趣区进行超声造影定量分析，进一步比较PTC颈部淋巴结转移组与未转移组CEUS特征的差异。结果 不同大小甲状腺乳头状癌CEUS特征（包括灌注强度、灌注均匀性及灌注缺损）差异有统计学意义（P < 0.05），颈部淋巴结转移组PTC结节CEUS定量参数（包括结节周边峰值强度、周边曲线下面积）均高于未转移组（P < 0.05），结节大小、结节内钙化类型、与被膜的关系在两组中差异有统计学意义（P < 0.05）。结论 不同大小甲状腺乳头状癌CEUS特征不同，CEUS定量分析技术对于评估甲状腺乳头状癌颈部淋巴结转移具有重要价值。 |
| 中文关键词:甲状腺乳头状癌 超声造影 淋巴结转移 |
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| Relationship between CEUS Characteristics and Cervical Lymph Node Metastasis in Different Sizes of Papillary Thyroid Carcinoma |
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| Abstract:Objective To investigate the relationship between contrast-enhanced ultrasound (CEUS) characteristics and cervical lymph node metastasis in different sizes of papillary thyroid carcinoma (PTC). Methods Ninety eight patients with suspicious thyroid nodules underwent conventional ultrasound and contrast-enhanced ultrasound.52 patients after local or total thyroidectomy with a histologically confirmed PTC. The CEUS characteristics of different size PTC were qualitatively evaluated, and we quantitatively analyzed of the region of interest in the edge and center of nodule respectively. CEUS characteristics in cervical lymph node metastasis group and non-metastasis group were further compared. Results The different size of papillary thyroid carcinoma revealed a significant difference (P<0.05) in CEUS characteristics. The edge of PTC nodules CEUS quantitative parameters (including peak intensity, PI; area under the curve, AUC) in cervical lymph node metastasis were higher than those non metastasis group (P<0.05), while the nodule size and nodular calcification showed statistically significant differences in two groups (P<0.05). Conclusion The CEUS features of different sizes of papillary thyroid carcinoma are different. CEUS quantitative analysis technique is of great value to evaluate the lymph node metastasis of papillary thyroid carcinoma. |
| keywords:Papillary thyroid carcinoma Contrast-enhanced ultrasound Lymph node metastasis |
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