| 甲状腺结节发生率及相关因素分析 |
| 投稿时间：2017-01-13 修订日期：2017-02-08 点此下载全文 |
| 引用本文：杨振宇,所佳宁,李艳波.甲状腺结节发生率及相关因素分析[J].医学研究杂志,2017,46(10):47-52 |
| DOI：
10.11969/j.issn.1673-548X.2017.10.013 |
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| 基金项目:国家卫生和计划生育委员会科教司公益性行业科研专项基金资助项目（201402005） |
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| 中文摘要:目的 调查分析黑龙江省城市和农村健康人群甲状腺结节的发生率及相关因素。方法 采用分层整群随机抽样的横断面调查方法，随机入户问卷调查，一般体格检查并行甲状腺超声检查，收集血液及尿液标本；甲状腺结节发生率以超声检出结节者为准。结果 黑龙江省城市和农村甲状腺结节发生率分别是27.77%和18.18%（χ2=33.991，P<0.01）；女性高于男性，随着患者年龄增加，甲状腺结节发生率显著增加（P<0.01）。另外，甲状腺结节患者的尿碘量、TSH水平、TPOAb阳性率、TgAb阳性率、收缩压、空腹血糖、甘油三酯、胆固醇、低密度脂蛋白和高密度脂蛋白显著高于正常人群，而糖化血红蛋白则显著下降（P<0.05）。Logistic多因素分析发现，地域分布、性别、年龄、胆固醇水平和糖化血红蛋白是影响甲状腺结节发生率的独立危险因素（P<0.05），其中黑龙江地域分布对甲状腺结节发生率的影响属首次发现。结论 黑龙江地区城市人群甲状腺结节发生率明显高于农村人群，女性又高于男性，随着年龄的增加其发生率也显著增加，其中地域分布、性别、年龄、胆固醇和糖化血红蛋白水平是影响甲状腺结节发生率的独立危险因素。 |
| 中文关键词:黑龙江 甲状腺结节 发生率 影响因素 |
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| Analysis of Incidence Rate and Related Factors of Thyroid Nodules |
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| Abstract:Objective To investigate and analysis the incidence rate and related factors of thyroid nodules in urban and rural health population in Heilongjiang Province. Methods A cross-sectional survey was conducted using stratified cluster random sampling. Carried on the random questionnaire survey, general physical examination and thyroid ultrasonography, collected blood and urine samples; The incidence of thyroid nodules was determined by ultrasound. Results The incidence of thyroid nodules in urban and rural of Heilongjiang Province was 27.77% and 18.18%, (χ2=33.991,P<0.01). women were higher than men. The incidence of thyroid nodules was significantly increased with the increase of age, (P<0.01).In addition, urinary iodine, TSH level, TPOAb, TgAb, systolic blood pressure, fasting blood glucose, triglyceride, cholesterol, low density lipoprotein and high density lipoprotein were significantly higher in patients with thyroid nodules than normal population(P<0.05).Logistic multivariate analysis showed that geographical distribution, gender, age, cholesterol levels and glycosylated hemoglobin were independent risk factors for the incidence of thyroid nodules (P<0.05),among which the influence of geographical distribution was found for the first time in Heilongjiang region. Conclusion The incidence of thyroid nodules in the urban was significantly higher than that of the rural in Heilongjiang Province, women were higher than men. The incidence of thyroid nodules was significantly higher with age. Geographical distribution gender, age, cholesterol and glycosylated hemoglobin level are independent risk factors for the incidence of thyroid nodules. |
| keywords:Heilongjiang Thyroid nodule Incidence rate Influencing factors |
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