| 幽门螺杆菌感染和老年颈动脉粥样硬化的关系 |
| 投稿时间：2017-02-15 修订日期：2017-03-10 点此下载全文 |
| 引用本文：程静,吴晓,董言斌,张静,洪波,何学明.幽门螺杆菌感染和老年颈动脉粥样硬化的关系[J].医学研究杂志,2017,46(11):128-131 |
| DOI：
10.11969/j.issn.1673-548X.2017.11.031 |
| 摘要点击次数: 1546 |
| 全文下载次数: 1108 |
|
|
| 中文摘要:目的 研究幽门螺杆菌（Hp）感染和老年颈动脉粥样硬化间的关系。方法 选取确诊为老年颈动脉粥样硬化250例，检测Hp感染状况、颈动脉粥样硬化程度、血清氧化型低密度脂蛋白（Ox-LDL）及各项血脂水平，对统计结果进行比较分析。结果 Hp感染组总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）及血清Ox-LDL各项指标水平与非Hp感染组比较，差异有统计学意义（P<0.05）；而重度Hp感染组TC、TG及血清Ox-LDL指标水平均明显高于轻度Hp感染组，且差异有统计学意义（P<0.05）；重度Hp感染组的动脉硬化程度达重度所占比例为52.78%，明显的高于非Hp感染组（6.92%）和轻度Hp感染组（23.81%），且差异均有统计学意义（P<0.05）。结论 幽门螺杆菌感染能够引起老年颈动脉粥样硬化患者血脂代谢紊乱，导致血脂水平升高。 |
| 中文关键词:幽门螺杆菌 颈动脉粥样硬化 血脂水平 总胆固醇 |
| |
| Relationship Between Helicobacter Pylori Infection and Aged Carotid Atherosclerosis |
|
|
| Abstract:Objective To study the relationship between Helicobacter pylori infection (Hp) and aged carotid atherosclerosis.Methods The condition of Hp infection, the degree of carotid atherosclerosis, oxidized low density lipoprotein (Ox-LDL) and the levels of serum lipids were measured in 250 aged carotid atherosclerosis patients diagnosed, and the statistical results were analyzed and compared.Results The levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and the serum Ox-LDL in the Hp infection group were significantly different from those of non-Hp infection group (P<0.05). The levels of TC, TG and the serum Ox-LDL in severe Hp infection group were significantly higher than those in mild Hp infection group (P<0.05). The degree of atherosclerosis in severe Hp infection group was 52.78%, which was significantly higher than that in mild Hp infection group (6.92%) and mild Hp infection (23.81%), and the difference was statistically significant (P<0.05).Conclusion Helicobacter pylori infection cause lipid metabolism disorders in elderly patients with carotid atherosclerosis, resulting in increased blood lipids. |
| keywords:Helicobacter pylori Carotid atherosclerosis Blood lipid levels Total cholesterol |
| 查看全文 查看/发表评论 下载PDF阅读器 |
