| 500例月经失调女性与200例健康体检女性泌乳素水平的分析比较 |
| 投稿时间：2016-12-13 修订日期：2017-01-18 点此下载全文 |
| 引用本文：吴云路,丁杰锋,刘琦,王立昌.500例月经失调女性与200例健康体检女性泌乳素水平的分析比较[J].医学研究杂志,2017,46(12):73-77 |
| DOI：
10.11969/j.issn.1673-548X.2017.12.019 |
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| 基金项目:浙江省卫生适宜技术成果转化计划项目（2016ZHB030）；浙江省医药卫生科技计划项目（2012KYB216） |
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| 中文摘要:目的 比较月经失调与健康女性泌乳素水平，为治疗月经失调提供理论依据。方法 收集笔者医院月经失调患者，按年龄分4组，健康女性为对照，统计高泌乳素血症在月经失调患者中的分布，各组高泌乳素血症比例、总体泌乳素平均水平、除去高泌乳素血后泌乳素平均水平。结果 ≤ 20岁、21~30岁：高泌乳素血症比例为14.80%（0），16.88%（6.25%）（括号内为健康组比例，下同）；月经失调组总体泌乳素平均水平高于健康组（P<0.05）；除去高泌乳素血，两组平均泌乳素水平差异无统计学意义（P>0.05）；31~40岁：高泌乳素血症比例为6.43%（3.33%），两组总体泌乳素平均水平差异无统计学意义（P>0.05），除去高泌乳素血，两组泌乳素水平差异无统计学意义（P>0.05）；41~50岁：高泌乳素血症的比例为6.86%（6.45%），两组总体泌乳素平均水平差异无统计学意义（P>0.05），除去高泌乳素血，月经失调组平均泌乳素水平显著低于健康组（P<0.05）。结论 高泌乳素血症主要出现在较为年轻的育龄女性；泌乳素主要以高泌乳素血症形式导致月经失调；对于月经失调的女性尤其是育龄女性，应注意其泌乳素水平。 |
| 中文关键词:月经失调 泌乳素 年龄段 高泌乳素血症 |
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| Comparison of Prolactin Levels between 500 Cases of Menstrual Disorder Women and 200 Cases of Healthy Physical Examination Women |
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| Abstract:Objective To compare the prolactin levels of menstrual disorder women and provide theoretical basis for treatment of menstrual disorders.Methods Collected patients diagnosed as menstrual discords in our hospital and divided them into four groups according to their age. The healthy physical examination women were as control. The distribution of hyperprolactinemia in menstrual disorders was analyzed. Calculate the proportion of high prolactin in each group, the average level of prolactin, and the average prolactin levels after removal of hyperprolactinemia samples.Results Under 20 and 21-30 years old groups:the proportion of patients with hyperprolactinemia in each group was 14.8% (0), 16.88% (6.25%), respectively (Value in brackets was proportion of hyperprolactinemia in healthy physical examination group); The average prolactin levels in the menstrual disorder groups were significantly higher than those in the physical examination groups (P<0.05). After removal of the hyperprolactinemia samples, the average prolactin levels of the two groups showed no significant difference. 31-40 years old group:the proportion of patients with hyperprolactinemia was 6.43% (3.33%). The average prolactin levels of two groups showed no significant difference (P>0.05). After removal of hyperprolactinemia samples, the average prolactin levels of two groups showed no significant difference (P>0.05). 41-50 years old group:the proportion of patients with hyperprolactinemia was 6.86% (6.45%). The average prolactin levels of two groups showed no significant difference (P>0.05). After removal of the hyperprolactinemia samples, the average prolactin level in the menstrual disorder groups was significantly lower than that in the healthy physical examination group (P<0.05).Conclusion Hyperprolactinemia occurs mainly in young women of childbearing age. Prolactin causes menstrual disorders mainly through the form of hyperprolactinemia. For women with menstrual disorders, especially women of childbearing age, attention should be paid to prolactin levels. |
| keywords:Menstrual disorder Prolactin Age groups Hyperprolactinemia |
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