| 磁敏感加权成像检测脑微出血及其与脑出血/腔隙性脑梗死研究 |
| 投稿时间：2017-10-15 修订日期：2017-10-20 点此下载全文 |
| 引用本文：金美玉,金洪国,严金岗,陈雅青,范艳芬,杨榕,寇雪莲.磁敏感加权成像检测脑微出血及其与脑出血/腔隙性脑梗死研究[J].医学研究杂志,2018,47(6):99-103 |
| DOI：
10.11969/j.issn.1673-548X.2018.06.023 |
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| 基金项目:浙江省医药卫生一般研究计划项目（2015KYA227） |
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| 中文摘要:目的 本研究明确脑出血/腔隙性脑梗死与脑微出血之间的关系。方法 搜集55例既往磁共振磁敏感成像显示脑微出血的患者，通过回顾性分析，评估脑出血/腔隙性脑梗死的位置是否与既往检测到的脑微出血位置一致。结果 其中34例脑出血，21例腔隙性脑梗死。腔隙性脑梗死位置与脑微出血相对应仅有1例（4.8%），脑出血相对应21例（61.8%）。在脑出血患者中，深部脑出血组对应比例（19/24，占79.2%）高于脑叶出血组（2/10，20%）。结论 脑出血和脑微出血之间的紧密位置关联表明，脑微出血代表容易出血的微血管病变。此外，深部脑出血组和脑叶出血组之间的不同的对应比率，可能归因于不同的发病机制。 |
| 中文关键词:磁敏感加权成像 脑出血 腔隙性脑梗死 脑微出血 |
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| Study on the Location Relationship Between Microbleeds and Intracerebral Hemorrhage/lacunar Infarction with Magnetic Sensitive Weighted Imaging |
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| Abstract:Objective To clarify the positional relationship between recurrent intracerebral hemorrhage/lacunar infarction and previously detected microbleeds. Methods We evaluated patients with recurrent intracerebral hemorrhage/lacunar infarction who had microbleeds, as shown on suceptibility-weighted MRI. We assessed retrospectively whether the location of recurrent intracerebral hemorrhage/lacunar infarction corresponded to that of the prior microbleed. Patients with intracerebral hemorrhage were divided into the deep intracerebral hemorrhage group and the lobar intracerebral hemorrhage group, and the positional relationship between hematoma and previously detected microbleeds was evaluated. Results A total of 55 patients, including 34 with recurrent intracerebral hemorrhage and 21 with recurrent lacunar infarction were evaluated. Although the location of the lacunar infarction corresponded to prior microbleeds in only 1 patient (4.8%), the location of intracerebral hemorrhage corresponded to prior locations of microbleeds in 21 patients (61.8%). Among the patients with intracerebral hemorrhage, the correspondence ratio was higher in the deep intracerebral hemorrhage group (19 of 24 patients, 79.2%) than in the lobar intracerebral hemorrhage group (2 of 10 patients, 20%). Conclusion The close positional association between recurrent intracerebral hemorrhage and prior microbleeds suggests that microbleeds represent hemorrhage-prone microangiopathy. In addition, different correspondence ratios between the deep intracerebral hemorrhage group and the lobar intracerebral hemorrhage group may be attributable to their different pathogenesis. |
| keywords:Susceptibility weighted imaging Intracerebral hemorrhage Lacunar infarction Microbleed |
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