超声弹性成像技术初步评价黄酒对动脉粥样硬化患者大动脉弹性的改善作用
投稿时间:2017-11-06  修订日期:2017-11-14  点此下载全文
引用本文:茹翱,季政,范晓华,沈艳,李金晶.超声弹性成像技术初步评价黄酒对动脉粥样硬化患者大动脉弹性的改善作用[J].医学研究杂志,2018,47(8):176-179
DOI: 10.11969/j.issn.1673-548X.2018.08.041
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作者单位
茹翱 313000 湖州市第一人民医院超声科 
季政 312000 浙江大学绍兴医院、绍兴市人民医院心内科 
范晓华 313000 湖州市第一人民医院超声科 
沈艳 313000 湖州市第一人民医院超声科 
李金晶 313000 湖州市第一人民医院超声科 
基金项目:湖州师范学院校级科研项目(2016XJXM58)
中文摘要:目的 应用超声弹性成像技术评价黄酒对动脉粥样硬化患者大动脉弹性的改善作用。方法 纳入经血管彩色多普勒超声诊断为动脉粥样硬化(AS)患者90例,另选取年龄和性别相匹配的40例志愿者作为正常对照组。AS患者随机分为AS对照组(n=45)和AS+黄酒组(n=45)并进行相应干预。干预前后各组均行颈动脉、股动脉血管彩色多普勒超声检查,测量血管壁内中膜厚度(IMT),血管阻力指数(RI);另采用超声弹性成像技术评估大动脉弹性,计算血管壁与血管内血液的应变率比值(B/A)。最后对各组资料进行对比研究。结果 干预前,AS对照组与AS+黄酒组IMT、RI、B/A值均高于正常对照组,差异有统计学意义(P<0.01)。干预后,AS+黄酒组RI、B/A值较AS对照组显著降低(P<0.05),IMT较AS对照组略降低(P>0.05),但上述指标仍高于正常对照组(P<0.01)。与干预前比较,干预后AS+黄酒组RI、B/A值较干预前显著降低(P<0.05),IMT较干预前略降低(P>0.05)。结论 黄酒对动脉粥样硬化患者大动脉弹性具有一定的改善作用,超声弹性成像技术可以方便、快捷、无创地评估大动脉弹性改变,具有重要的临床意义。
中文关键词:黄酒  超声弹性成像  动脉粥样硬化
 
Preliminary Evaluation of the Improved Efficacy of Chinese Rice Wine on the Elasticity of Large Artery in Patients with Atherosclerosis by Using Ultrasonic Elasticity Imaging
Abstract:Objective To investigate the improving effect of chinese rice wine on the elasticity of large artery in patients with atherosclerosis by using ultrasonic elasticity imaging. Methods Ninety patients diagnosised of atherosclerosis(AS) by vascular color doppler ultrasonography were enrolled in the study, and another 40 volunteers matched for age and sex were selected as normal control group.The AS patients were randomly divided into two groups and processed as follows:AS control group and AS + Chinese Rice Wine group. Before and after the intervention, all groups underwent color Doppler ultrasound examination in the carotid artery and femoral artery. We measured the vascular wall intima-media thickness (IMT) and vascular resistance index (RI). With the ultrasound elasticity imaging,we assessed large artery elasticity and calculated the strain ratio (B/A) of vessel wall and blood. Finally, the data of each group were compared. Results Before intervention, IMT, RI and B/A in the AS control group and AS + Chinese Rice Wine group were significantly higher than in the normal control group (P<0.01). After intervention, RI and B/A in the AS + Chinese Rice Wine group were significantly decreased than in the AS control group (P<0.05), and IMT was a little decreased(P>0.05). But the above indexes remain higher than in the normal control group(P>0.05). Compared with before intervention, RI and B/A in the AS + Chinese Rice Wine group were significantly decreased(P<0.05), and IMT was a little decreased(P>0.05). Conclusion Chinese Rice Wine has a certain effect on the improvement of the elasticity of large artery in patients with atherosclerosis, which can be evaluated by the ultrasonic elasticity imaging conveniently, rapidly and noninvasively.
keywords:Chinese Rice Wine  Ultrasonic Elasticity Imaging  Atherosclerosis
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