| 艾灸联合鼠神经生长因子治疗糖尿病神经源性膀胱的疗效分析 |
| 投稿时间：2017-11-29 修订日期：2017-12-13 点此下载全文 |
| 引用本文：陈宗存,符沙沙,陈金逸,符茂雄,吴祖荣,黄亚莲.艾灸联合鼠神经生长因子治疗糖尿病神经源性膀胱的疗效分析[J].医学研究杂志,2018,47(9):109-111,108 |
| DOI：
10.11969/j.issn.1673-548X.2018.09.025 |
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| 基金项目:海南省自然科学基金资助项目（817333）；海南省卫生计生行业科研项目（16A200071） |
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| 中文摘要:目的 探讨艾灸联合鼠神经生长因子治疗糖尿病神经源性膀胱的疗效。方法 选取2012年1月~2017年5月在笔者医院内分泌科住院的糖尿病神经源性膀胱患者120例，采用数字表法随机分为3组，每组各40例。其中A组接受降血糖、导尿、排尿训练等常规治疗，B组在常规治疗基础上加用鼠神经生长因子治疗，C组在常规治疗基础上加用艾灸联合鼠神经生长因子治疗。治疗4周后，比较各组症状、膀胱残余尿及腓神经感觉转导速度变化情况。结果 3组患者治疗前一般情况差异无统计学意义。治疗后，B组和C组的总有效率高于A组（72.5%，85.0% vs 35.0%），膀胱残余尿量少于A组（98.4±21.3ml， 87.2±17.6ml vs 137.1±19.6ml），腓神经感觉转导速度高于A组（47.83±6.37m/s， 51.36±4.28m/s vs 44.36±5.24m/s，P均<0.05）。治疗后，C组膀胱残余尿少于B组（87.2±17.6ml vs 98.4±21.3ml），腓神经转导速度高于B组（51.36±4.28m/s vs 47.83±6.37m/s，P均<0.05）。结论 艾灸联合鼠神经生长因子能有效改善糖尿病神经源性膀胱病情，且安全性较好，值得临床上推广应用。 |
| 中文关键词:艾灸 鼠神经生长因子 神经源性膀胱 2型糖尿病 |
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| Effects of Diabetic Neurogenic Bladder Were Treated by Moxibustion Combined with Nerve Growth Factor |
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| Abstract:Objective To observe the effect of moxibustion combined with nerve growth factor (NGF) on treating diabetic neurogenic bladder (DNB). Methods From January 2012 to May 2017, 120 diabetic neurogenic bladder patients were randomly divided into A, B and C groups with 40 cases in each group, based on routine treatment of diabetes. The A group was given urination training, the B group was given NGF, the C group was given moxibustion combined with NGF. The symptom, bladder residual urine volume and nerve conduction velocity of peronaeus were observed before and after treatment. Results Compared to the A group, the B and C group had higher effective rate(72.5%,85.0% vs 35.0%), lower bladder residual urine volume(98.4±21.3ml, 87.2±17.6ml vs 137.1±19.6 ml) and higher nerve conduction velocity(47.83±6.37m/s, 51.36±4.28m/s vs 44.36±5.24m/s,all P<0.05). The C group had lower bladder residual urine volume(87.2±17.6ml vs 98.4±21.3ml) and higher nerve conduction velocity than the B group(51.36±4.28m/s vs 47.83±6.37m/s) (P<0.05). Conclusion It has significant therapeutic effect and safety of using moxibustion combined with with nerve growth factor. |
| keywords:Moxibustion Nerve growth factor Neurogenic bladder Type 2 diabetes |
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