| 原发性干燥综合征合并冠心病患者接受冠状动脉介入治疗术后的长期预后分析 |
| 投稿时间：2018-03-15 修订日期：2018-03-23 点此下载全文 |
| 引用本文：周力,陈晖,李东宝,赵慧强,姚道阔,李虹伟.原发性干燥综合征合并冠心病患者接受冠状动脉介入治疗术后的长期预后分析[J].医学研究杂志,2018,47(11):151-154,179 |
| DOI：
10.11969/j.issn.1673-548X.2018.11.033 |
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| 中文摘要:目的 分析合并原发性干燥综合征（pSS）的冠状动脉性心脏病（CAD）患者接受经皮冠状动脉介入治疗术（PCI）后的长期预后。方法 收集43例自2009年1月~2013年12月在首都医科大学附属北京友谊医院接受PCI治疗的pSS患者的临床资料，回顾性分析pSS患者的临床表现、冠状动脉病变特点，并对入选患者进行平均3年的长期随访。结果 43例患者中有34例（79.1%）具有≥2个传统冠心病危险因素，其中以高血压、高脂血症最为多见。74.4%的患者冠状动脉弥漫性长病变（>30mm），平均SYNTAX 积分为29.6±6.2。入选患者共置入78枚药物涂层支架。术后平均3年随访期间因心力衰竭再入院累积发生率高达23.3%。结论 合并pSS的CAD患者冠状动脉病变以弥漫性长病变为主；此类患者接受PCI治疗后以心力衰竭再入院多见。 |
| 中文关键词:原发性干燥综合征 冠状动脉性心脏病 经皮冠状动脉介入治疗术 |
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| Prognosis in Patients with Primary Sjögren's Syndrome Underwent Percutaneous Coronary Intervention |
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| Abstract:Objective To report long-term clinical prognosis in a consecutive series of patients with coronary atery disease (CAD) and primary Sjögren's syndrome (pSS) who underwent percutaneous coronary intervention (PCI). Methods The study group comprised 43 consecutive patients with pSS who underwentPCI in Beijing Friendship Hospital between January 2009 and December 2013. Medical records were analyzed retrospectively including clinical basic material, coronary angiogram data, and the incidence of major adverse cardiac events (MACE) during the longterm (median 3 years) followup. Results Thrityfour of the patients (79.1%) had two or more traditional CAD risk factors. And hypertension and hyperlipidemia are the most common. Long diffuse lesions (>30mm) were present in more than 2/3 of patients (74.4%), and the average SYNTAX score was 29.6±6.2. Seventy-eight drugeluting stents were implanted. After a median followup period of 3 years, cumulative incidence of heart failure requiring rehospitalization is 23.3%. Conclusion Patients with pSS and CAD may have long diffuse lesions. PCI in these patients tends to result in an increased rate of heart failure requiring rehospitalization during long-term follow-up. |
| keywords:Primary Sjögren's syndrome Coronary artery disease Percutaneous coronary intervention |
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