高同型半胱氨酸血症脑梗死患者的相关特征分析
投稿时间:2022-11-25  修订日期:2022-12-06  点此下载全文
引用本文:石奕虹,李晶,王敏.高同型半胱氨酸血症脑梗死患者的相关特征分析[J].医学研究杂志,2024,53(1):41-44
DOI: 10.11969/j.issn.1673-548X.2024.01.010
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作者单位
石奕虹 天津中医药大学第一附属医院、国家中医针灸临床医学研究中心 通信作者:李晶,电子信箱:309483398@qq.com〖JZ 300193 
李晶 天津中医药大学第一附属医院、国家中医针灸临床医学研究中心 通信作者:李晶,电子信箱:309483398@qq.com〖JZ 300193 
王敏 天津中医药大学第一附属医院、国家中医针灸临床医学研究中心 通信作者:李晶,电子信箱:309483398@qq.com〖JZ 300193 
基金项目:国家自然科学基金资助项目(81674056);天津市自然科学基金资助项目 (18JCYBJC94200)
中文摘要:目的 探讨脑梗死患者中高同型半胱氨酸血症者的常见症状和伴随疾病特征及其影响因素的相关性分析。方法 将血同型半胱氨酸≥15μmol/L的患者列为高同型半胱氨酸血症脑梗死组(H组),共151例;血同型半胱氨酸<15μmol/L的患者列为血同型半胱氨酸正常脑梗死组(N组),共86例,比较两者的症状差异及其影响因素。结果 在脑梗死患者中,H组患者的年龄大(P=0.049)、男性多(P=0.002),具有吸烟史(P=0.025)、糖尿病(P=0.008)、高脂血症(P=0.034)、叶酸缺乏(P=0.002)并伴随认知障碍(P=0.009)、语言障碍(P=0.043)的比例高。通过二元Logistic回归分析,得到年龄(P=0.023)、糖尿病(P=0.018)、叶酸缺乏(P=0.026)、认知障碍(P=0.019)均为高同型半胱氨酸血症的相关影响因素。结论 合并高同型半胱氨酸血症的脑梗死患者表现为老年,多数合并患有糖尿病、叶酸缺乏和认知障碍。
中文关键词:脑梗死 高同型半胱氨酸血症 叶酸缺乏
 
Study on Self-management Level of Elderly Diabetic Mellitus Patients in Dongcheng District of Beijing and Its Influencing Factors
Abstract:Purpose/Significance To investigate the status quo and influencing factors of self-management level of elderly diabetic mellitus patients in Dongcheng District of Beijing, and to provide references for further development of community diabetes health education and health management. Method/Process The survey is conducted on 1 962 cases of elderly patients with type 2 diabetes mellitus who are randomly selected from community-level health service institutions in Dongcheng District of Beijing and are investigated by self-made questionnaires and the summary of diabetes self-care activities. Multiple stepwise regression and logistic regression are used to analyze the influencing factors of patients’ self-management level.Result/Conclusion The self-management level of elderly diabetic mellitus patients is affected by many factors, among which the awareness of disease-related knowledge, the form of medical security and the use of health-related software to manage chronic diseases are the main influencing factors(P<0.05). Local management departments can take targeted health interventions to further improve the self-management ability of elderly diabetic mellitus patients.
keywords:type 2 diabetes mellitus  self-management  influencing factors
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