| 心搏骤停后综合征患者血浆渗透压测定的临床意义 |
| 投稿时间：2014-12-03 修订日期：2014-12-25 点此下载全文 |
| 引用本文：张迪,陈伟,余追,周晨亮,周青山.心搏骤停后综合征患者血浆渗透压测定的临床意义[J].医学研究杂志,2015,44(6):94-97 |
| DOI：
10.11969/j.issn.1673-548X.2015.06.026 |
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| 中文摘要:目的 探讨心搏骤停后综合征患者血浆渗透压的变化及临床意义。方法 选取心搏骤停后综合征患者36例,其中死亡组22例,生存组14例,选取健康体检者20例为对照组,测定3组患者入院时血浆渗透压和急性生理学与慢性健康状况Ⅱ(APACHE Ⅱ)评分。结果 与对照组相比,死亡组血浆渗透压明显升高(P<0.05),而生存组则无明显差异;两组患者APACHE Ⅱ评分明显升高,差异有统计学意义(P<0.05)。死亡组血浆渗透压和APACHE Ⅱ评分明显高于生存组,差异有统计学意义(P<0.05)。生存组血浆渗透压异常率为14.29%,死亡组血浆渗透压异常率为68.18%(P<0.05)。心搏骤停后综合征患者血浆渗透压与APACHE Ⅱ评分呈正相关(r=0.804,P<0.05)。结论 心搏骤停后综合征死亡患者血浆渗透压明显升高,动态监测血浆渗透压有助于评估心搏骤停后综合征患者的病情危重程度及预后。 |
| 中文关键词:心搏骤停后综合征 渗透压 预后 |
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| Clinical Significance of Plasma Osmolality Measurement in Patients with Post-cardiac Arrest Syndrome |
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| Abstract:Objective To explore the clinical significance of plasma osmolality measurement in patients with post-cardiac arrest syndrome. Methods A total of 36 patients with post-cardiac arrest syndrome were selected. The patients were divided into death group (n=22) and survival group (n=14) according to prognosis. 20 subjects undergoing health check were served as control group. The level of plasma osmolality was detected and acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ) scores were estimated in all the patients at admission. Results The plasma osmolality level was significantly higher in death group than in control group (P<0.05) whereas there was no difference in survival group. The APACHE Ⅱ score was significantly higher in two groups than in control group (P<0.05). The plasma osmolality level and the APACHE Ⅱ score were higher in death group than in survival group (P<0.05). The abnormal rate of plasma osmolality in survival group was 14.29%, whereas it was 68.18% in death group (P<0.05). The plasma osmolality level was positively related with APACHE Ⅱ score in patients with post-cardiac arrest syndrome (r=0.804,P<0.05). Conclusion The plasma osmolality level was increased significantly in death group patients with post-cardiac arrest syndrome and could be used for the assessment of their severity of illness and the prognosis. |
| keywords:Post-cardiac Arrest syndrome Osmolality prognosis |
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