| 尿α1-微球蛋白筛查意义及其危险因素分析 |
| 投稿时间：2014-12-30 修订日期：2015-01-21 点此下载全文 |
| 引用本文：李燕燕,马清.尿α1-微球蛋白筛查意义及其危险因素分析[J].医学研究杂志,2015,44(9):85-87 |
| DOI：
10.11969/j.issn.1673-548X.2015.09.023 |
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| 中文摘要:目的 尿α1-MG作为早期肾损害标志物,对其进行筛查可早期发现慢性肾脏病,通过对肾功能在CKD G3期以上尿α1-MG进行分析,为早期筛查CKD提供理论依据。 方法 对982例健康体检尿常规蛋白为阴性的人群,对其尿α1-MG进行统计学分析。 结果 尿α1-MG的阳性率为25.3%,阳性与高血压、糖尿病、冠心病、糖化血红蛋白水平、空腹血糖水平、高甘油三脂、低高密度脂蛋白胆固醇、吸烟、饮酒有关,其中高血压、空腹血糖、吸烟是其独立危险因素。 结论 在尿蛋白为阴性的情况下,对高危人群需行尿α1-MG检查是十分必要的。 |
| 中文关键词:慢性肾脏病 肾小管间质损害 尿α1-MG 肾功能进展 |
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| Significance of Early Screening Urinary α1-MG and the Risk Fators of It |
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| Abstract:Objective To provide the theory basis for CKD diagnosis, through the study of the samples' urinary α1-MG whose classification of renal function is between CKD G1-3. Methods Totally 982 samples were took into account whose PRO were negative.The α1-MG were statistical analysed. Results The positive rate of urinary α1-MG was 25.3%.It was followed with hypertension, diabetes,coronary heart disease, glycosylated hemoglobin, fasting blood-glucose, high triglycerides, low HDL cholesterol, smoking and drinking.Hypertension and smoking were the independent risk factors. Conclusion It is very necessary to test urinary α1-MG for high-risk grous, in the case of urinary protein were negative. |
| keywords:Chronic kidney disease Damage of the renal tubular Urinary α1-MG Progress of kidney function |
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