| 降压0号治疗高血压对抑郁情绪的影响 |
| 投稿时间：2016-10-12 修订日期：2016-10-31 点此下载全文 |
| 引用本文：曹亚英,武轶群,秦雪英,任涛,胡永华.降压0号治疗高血压对抑郁情绪的影响[J].医学研究杂志,2017,46(6):56-59 |
| DOI：
10.11969/j.issn.1673-548X.2017.06.015 |
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| 基金项目:国家"十一五"科技支撑项目[2006BAI01A03-（16）] |
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| 中文摘要:目的 研究降压0号对高血压患者抑郁情绪的影响。方法 采用现场实验的方法，将研究对象分为降压0号组和常规治疗组，进行为期1年的降压治疗。研究对象在基线和随访1年末均自填衡量抑郁程度的Zung量表。结果 降压0号组和常规治疗组分别纳入1445例和1414例研究对象。随访1年末两组血压达标率分别为80.6%和81.8%（P=0.439）。随访期间，两组量表评分均略有增加（P均<0.05）但变化幅度小且差异无统计学意义（P=0.429），两组有抑郁倾向者比例均无明显变化（P均>0.05）。结论 与其他常规降压药物相比，未发现降压0号治疗高血压对患者的抑郁情绪有明显影响。 |
| 中文关键词:降压0号 抑郁 高血压 |
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| Influence of Anti-hypertension No. 0 on Depression in Treatment of Hypertension |
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| Abstract:Objective To explore the influence that anti-hypertension No.0 might exert on depression in the treatment of hypertension. Methods Participants were divided into anti-hypertension No.0 group and control group taking other antihypertensive agents in a field trial, and were followed up for one year. Zung Self-Rating Depression Scale was took both at baseline and one year after by participant themselves, which was used for measuring depression level. Results A total of 1445 participants were recruited in anti-hypertension No.0 group and 1414 in control group. After one year of treatment, the control rates of hypertension were 80.6% and 81.8% in anti-hypertension No.0 group and control group, respectively (P=0.439). During follow-up, the Zung Scale score increased slightly in both anti-hypertension No.0 group and control group (both P<0.05), without significant differences between the two groups (P=0.429). No significant differences were observed in the percentages of participants having depressive tendency in these two groups (both P>0.05). Conclusion Compared with other conventional medicines for hypertension, no significant influence on depression was found for hypertensive patients taking Anti-hypertension No.0. |
| keywords:Anti-hypertension No.0 Depression Hypertension |
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