| 介入相关性心肌梗死与预后的关系 |
| 投稿时间：2016-02-27 修订日期：2017-03-01 点此下载全文 |
| 引用本文：王彦涵,耿金,魏忠海,戴庆,王涟,宋杰.介入相关性心肌梗死与预后的关系[J].医学研究杂志,2017,46(10):88-92 |
| DOI：
10.11969/j.issn.1673-548X.2017.10.023 |
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| 基金项目:江苏省卫生厅基金资助项目（H201436） |
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| 中文摘要:目的 研究经皮冠状动脉介入治疗（percutaneous coronary intervention，PCI）术后发生介入相关性心肌梗死对预后的影响。方法 选择行PCI术治疗的患者共360例，根据是否发生介入相关性心肌梗死分为心肌梗死组及非心肌梗死组，观察术后6个月超声心动图较术前相比左心室射血分数变化量（△LVEF）以及随访过程中主要不良心血管事件（the major adverse cardiovascular events，MACE）发生率。结果 △LVEF心肌梗死组与非心肌梗死组比较差异有统计学意义（P=0.002）；MACE发生率心肌梗死组与非心肌梗死组比较差异有统计学意义（P=0.004）；分层分析示，对于非旋磨患者，介入相关性心肌梗死与△LVEF （P=0.000）及MACE （P=0.004）相关，在旋磨患者中，介入相关性心肌梗死与△LVEF （P=0.857）及MACE （P=0.241）未见同样的相关性。结论 介入相关性心肌梗死对于非旋磨的患者发生左心室射血分数下降、MACE发生具有预测价值，在旋磨患者中则并未显示相应的预测性。 |
| 中文关键词:经皮冠状动脉介入治疗 经皮冠状动脉内旋磨术 介入相关性心肌梗死 |
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| Prognostic Significance of Procedure-related Myocardial Infarction:A Retrospective Study |
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| Abstract:Objective To study the prognostic relevance of procedure-related myocardial infarction(PMI) in patients experienced percutaneous coronary intervention(PCI). Methods A total of 360 patients experienced PCI treatment were divided into myocardial infarction(MI) group and non-MI group on the basis of occurrence of PMI. The change in left ventricular ejection fraction(△LVEF) 6 months after PCI and the follow-up period major adverse cardiovascular events(MACE) rates were collected. Results There were statistical significant differences between the two groups on △LVEF (P=0.002) and occurrence rate of MACE (P=0.004); Stratified analysis showed PMI was related to △LVEF (P=0.000) and occurrence rate of MACE (P=0.004) in patients without percutaneous coronary rotational atherectomy(PTCRA), but in patients experienced PTCRA, PMI didn't show the same relevance to △LVEF (P=0.857) and MACE (P=0.241). Conclusion PMI is indicated prognostic value of △LVEF and occurrence rate of MACE in non-PTCRA patients, and corresponding association is not found in PTCRA parients. |
| keywords:Percutaneous coronary intervention Percutaneous coronary rotational atherectomy Procedure-related myocardial infarction |
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