| Abstract:Objective To investigate the correlation between diffusion tensor imaging (DTI) parameters and cognitive impairment in patients with cerebral hemorrhage (CMBs). Methods Totally 98 patients with cerebral hemorrhage in the Department of neurology were collected as observation group.In addition, 80 cases of brain micro bleeding were detected in our hospital as the control group.Daily life ability scale (ADL) was used to assess daily life.The Montreal cognitive rating scale (MoCA) was used to assess the cognitive function of the subjects.All subjects were performed by DTI imaging test.The number and distribution of CMBs lesions were observed. The correlation of two groups of MoCA and ADL score, DTI parameter, FA, MD value and MoCA score were analyzed by Pearson. Results A total of 325 CMBs lesions were detected.The basal ganglia area was 44.31%,cerebral cortex and cortex was accounted for 26.46%,thalamus was 8.31%,white matter was 8%,cerebellum was 6.77%,and brainstem was 6.15%.The FA value of the white matter, thalamus and cerebellum in the observation group was lower than that in the control group, and the MD value was higher than that of the control group,and the difference was statistically significant (P<0.05).The spatial execution ability, naming ability, memory, attention, abstraction ability, language, orientation ability and total score of the observation group were lower than those of the control group, the difference was statistically significant (P<0.05).In observation group, ADL walking, transfer, up and down stairs and other scores and total score were lower than the control group, the difference was statistically significant (P<0.05).Pearson correlation analysis showed that the MoCA scores included spatial execution ability, naming ability, memory, attention, abstraction, language, orientation ability and total score was positively correlated with the FA of basal ganglia, cerebral cortex, white matter, thalamus, cerebellum and brainstem, and negatively correlated with MD. Conclusion DTI detection, FA value, MD value and CMBs score of patients with MoCA have some relevance, which can be used to guide the recovery of cognitive impairment. |
