| 超声造影在肝癌TACE术后残留诊治中的价值 |
| 投稿时间：2017-12-17 修订日期：2017-12-27 点此下载全文 |
| 引用本文：李红学,刘军杰,胡巧琴,李航.超声造影在肝癌TACE术后残留诊治中的价值[J].医学研究杂志,2018,47(10):57-60 |
| DOI：
10.11969/j.issn.1673-548X.2018.10.016 |
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| 基金项目:广西壮族自治区自然科学基金资助项目（2016GXNSFBA380194，2017GXNSFBA198232）；广西壮族自治区医疗卫生适宜技术开发与推广应用项目（S201632）；广西医科大学青年科学基金资助项目（GXMUYSF201401） |
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| 中文摘要:目的 探讨超声造影（CEUS）在原发性肝癌TACE术后残留诊治中的价值。方法 对65个经DSA验证的TACE术后残留原发性肝癌（PLC）病灶，行CEUS检查，明确其位置和CEUS特征，指导制定合理的经皮微波消融治疗（PMCT）方案，分析消融疗效并随访其2年生存率。结果 PMCT消融1个月内肿瘤直径未见明显变化，超声造影评估PLC疗效与DSA有很好的一致性；TACE术后残留病灶经PMCT治疗后完全消融率为96.9%，AFP均有不同程度的降低，术后未见严重并发症；其6个月、1年、1年半和2年的生存率分别为87.7%、70.8%、53.8%和43.1%。结论 CEUS准确显示了TACE术后PLC残存病灶的血流灌注特征，为准确制定PMCT方案和治疗策略提供了很大的帮助，CEUS和DSA在PLC疗效评估方面有很好的一致性，CEUS逐渐成为PLC消融方案制定和疗效评估不可或缺的影像学方法。 |
| 中文关键词:超声造影 原发性肝癌 经导管动脉化疗栓塞 术后残留诊治 |
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| Value of Contrast-Enhanced Ultrasound in the Residual Diagnosis and Treatment of Primary Liver Cancer after TACE |
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| Abstract:Objective To investigate the value of CEUS in the diagnosis and treatment of primary liver cancer after TACE. Methods Sixty-five DSA-confirmed residual PLC lesions after TACE were examined by contrast-enhanced ultrasound and their location and contrast-enhanced characteristics were evaluated. The rational PMCT ablation protocol was established and the 2-year survival rate was analyzed. Results There was no significant changes of tumor size in 1 month after PMCT ablation. The contrast echocardiography was used to evaluate the efficacy of PLC in DSA. The complete ablation rate of residual tumor after TACE was 96.9%.To some extent, the AFP was decreased and no serious complications were found after operation. The 6-month, 1-year, 1.5-year and 2-year survival rates were 87.7%, 70.8%, 53.8% and 43.1% respectively. Conclusion CEUS accurately displays the perfusion characteristics of residual PLC after TACE, which provided a great help for the accurate PMCT ablation strategy and treatment strategy. CEUS and DSA have a good consistency in the evaluation of PLC efficacy and CEUS gradually becomes PLC ablation program development and evaluation of the effects of imaging indispensable methods. |
| keywords:CEUS PLC TACE Postoperative residue Diagnosis and treatment |
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