| TAMIS术治疗男性直肠癌的肿瘤学疗效及生存分析 |
| 投稿时间：2017-11-13 修订日期：2017-12-27 点此下载全文 |
| 引用本文：宋志岗,刘帅,连彦军,薛志广,宋炳辉.TAMIS术治疗男性直肠癌的肿瘤学疗效及生存分析[J].医学研究杂志,2018,47(10):107-110 |
| DOI：
10.11969/j.issn.1673-548X.2018.10.029 |
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| 基金项目:河北省邢台市科技计划项目（2017ZC085） |
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| 中文摘要:目的 观察经肛门微创手术（TAMIS）治疗男性直肠癌的肿瘤学疗效及生存率。方法 纳入2012年2月~2014年2月于笔者医院接收的84例直肠癌患者（男性）为对象，采用数字表法随机分成两组，其中观察组42例行TAMIS术，对照组42例接受传统经肛门局部切除术，观察两组手术治疗情况（术中出血量、肿瘤距肛门距离、手术时间、住院天数、并发症）及术后恢复情况（术后首次排气时间、首次排便时间、开始进食时间、下床活动时间）与远期疗效（局部复发率、远处转移率及生存率）。结果 观察组术中出血量明显低于对照组，且住院天数及手术时间均短于对照组，差异有统计学意义（P<0.05）；观察组并发症发生率（9.52%）低于对照组（38.09%），差异有统计学意义（P<0.05）；观察组局部复发率、远处转移率及生存率分别为4.76%、2.38%、95.24%，对照组依次为2.38%、2.38%、92.86%，差异均无统计学意义（P>0.05）。结论 TAMIS可获得与传统经肛门局部切除术相似的疗效及远期预后改善，但其手术微创性更佳，术后恢复更快，可作为优选手术方案。 |
| 中文关键词:TAMIS术 男性 直肠癌 肿瘤学 生存率 |
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| Oncological Efficacy and Survival Analysis of TAMIS for the Treatment of Male Rectal Cancer |
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| Abstract:Objective To evaluate the oncological efficacy and survival rate of transanal minimally invasive surgery (TAMIS) for male rectal cancer. Methods Eighty four patients with rectal cancer were enrolled from April 2012 to February 2014 in our hospital received (male) as the object, according to the random number table is divided into 2 groups, the observation group of 42 patients with TAMIS, 42 cases in the control group received conventional transanal local excision, observe two groups of surgical treatment (blood, tumor distance from the anus, operation time, hospitalization stay, complications of intraoperative and postoperative recovery) (postoperative first exhaust time, first defecation time, feeding time, ambulation time) and long-term efficacy (local recurrence rate, distant metastasis rate and survival rate). Results The amount of bleeding in the observation group was significantly lower than that of the control group, and the days of hospitalization and operation time were shorter than those in the control group. The difference was statistically significant (P<0.05). The complication rate of the observation group (9.52%) than in the control group (38.09%), and the difference was statistically significant (P<0.05). The observation group of local recurrence rate, distant metastasis rate and survival rate were 4.76%, 2.38%, 95.24%, the control group were 2.38%, 2.38% and 92.86%. There were no significant differences (P>0.05). Conclusion TAMIS can achieve similar curative effect and long-term prognosis with traditional transanal local resection, but its minimally invasive surgery is better, and postoperative recovery is faster, which can be used as the preferred surgical scheme. |
| keywords:TAMIS Men Rectal cancer Oncology Survival rates |
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