| 中国老年人夜间睡眠时间与认知障碍的相关性研究 |
| 投稿时间：2024-06-22 修订日期：2024-08-05 点此下载全文 |
| 引用本文：宋悦,田峻,舒晴,廖荣,赖郅昊,鲁薇薇.中国老年人夜间睡眠时间与认知障碍的相关性研究[J].医学研究杂志,2025,54(1):134-138, 162 |
| DOI：
10.11969/j.issn.1673-548X.2025.01.025 |
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| 中文摘要:目的 探讨中国65岁以上的老年人夜间睡眠时间与认知障碍的相关性。方法 基于CLHLS数据库的横断面分析,统计目标人群的相关基线资料,睡眠时间以问卷的方式采集,以7~8h作为参照,将其划分为睡眠不足、睡眠正常、睡眠过长。简易精神状态检查表(minimum mental state examination,MMSE)用于评定老年人的认知功能,采用Logistic回归分析探讨睡眠时间与认知障碍的相关性。结果 本研究最终纳入11113例研究对象,睡眠不足者4142例(37.3%)；睡眠正常者4065例(36.6%)；睡眠过长者2906例(26.1%)；认知障碍检出率为28.6%(3178/11113)。散点图结果表明,睡眠时间与认知功能呈非线性相关。调整相关混杂因素后,结果表明,睡眠不足和睡眠过多均会导致认知障碍的风险增加。限制性立方样条(restricted cubic spline,RCS)模型观察结果提示,老年人夜间睡眠时间与认知障碍的关系呈近似“U”形曲线关系,且睡眠时长控制在5.4~7.2h时,发生认知障碍的风险最低。结论 夜间睡眠不足、睡眠过长均会增加中国65岁以上的老年人认知障碍的风险,故应鼓励老年人选择最佳睡眠时间,降低认知障碍的发生。 |
| 中文关键词:老年人 睡眠时间 认知障碍 |
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| Correlation Between Nighttime Sleep Duration and Cognitive Dysfunction in Chinese Elderly. |
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| Abstract:Objective To investigate the correlation between nighttime sleep duration and cognitive dysfunction in Chinese elderly over 65 years. Methods Based on cross-sectional analysis of CLHLS database, the relevant baseline data of the target population were collected, sleep duration was collected by questionnaire, and 7-8h was used as a reference to divide it into three categories:insufficient sleep, normal sleep, and excessive sleep. Minimum mental state examination (MMSE) was used to assess cognitive dysfunction in elderly and Logistic regression analysis was used to explore the correlation between sleep duration and cognitive dysfunction. Results A total of 11113subjects were enrolled in this study, among whom 4142 (37.3%) subjects were insufficient sleep, 4065 (36.6%) subjects were normal sleep, and 2906 (26.1%) subjects were excessive sleep. The detection rate of cognitive impairment was 28.6%(3178/11113). The scatterplot results showed that sleep duration was nonlinearly correlated with cognitive function. After adjusting for related confounding factors, both insufficient and excessive sleep were associated with an increased risk of cognitive dysfunction. The restricted cubic spline (RCS) model suggested that there was an approximate U-shaped relationship between nighttime sleep duration and the risk for cognitive dysfunction, and the risk of cognitive dysfunction was lowest when the sleep duration was controlled between 5.4h and 7.2h.Conclusion Both insufficient and excessive sleep at night increase the risk of cognitive dysfunction, so the optimal sleep duration should be encouraged to reduce the occurrence of cognitive dysfunction. |
| keywords:Elderly Sleep duration Cognitive dysfunction |
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