| 构建《女性更年期综合征中西医结合诊疗指南》证据体——循证中医药实践 |
| 投稿时间：2024-11-02 修订日期：2024-11-21 点此下载全文 |
| 引用本文：方舒涵,黄旭春,曹晓静,成芳平,宋雷,李灵通,王小云.构建《女性更年期综合征中西医结合诊疗指南》证据体——循证中医药实践[J].医学研究杂志,2025,54(5):67-72 |
| DOI：
10.11969/j.issn.1673-548X.2025.05.013 |
| 摘要点击次数: 3 |
| 全文下载次数: 3 |
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| 基金项目:国家自然科学基金资助项目(82004411)；国家重点研发计划项目(2018YFC1704102)；第七批全国老中医药专家学术经验继承工作项目｛国中医药办人教函〔2021〕272号｝；王小云全国名老中医药专家传承工作室建设项目｛[2016]42｝；广东省中医院项目岭南妇科流派传承工作室建设项目｛[2013]233｝；广东省中医证候临床研究重点实验室(2017B030314166)；广东省中医院中医药科学技术研究专项｛[2023]194｝ |
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| 中文摘要:目的 构建《女性更年期综合征中西医结合诊疗指南》(下文简称“本指南”)的证据体,为推荐意见的形成提供有效证据支持。方法 根据循证指南的制订方法和规范,通过PICO(population, intervention, comparison, outcome)原则构建指南问题后,采用系统检索策略,从国内外数据库中筛选2022年7月30日前发表的中西医治疗更年期综合征相关文献,根据纳排标准确定纳入证据文献,应用ReviewManager5.3软件进行整合分析,采用GRADE方法进行证据分级质量评价。结果 共检索到143322篇文献,最终纳入92篇,涉及经典方、中成药、特色疗法等治疗措施,提取以上文献证据资料进行综合和分级,最终形成基础问题及临床问题的证据概要表。结论 本指南证据体的构建过程是一项循证中医药的探索性实践,本文梳理了其中重要环节,以期为中医药临床实践指南的制/修订工作提供参考。 |
| 中文关键词:循证医学 更年期综合征 中西医结合 指南 |
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| Constructing the Body of Evidence for the "Guidelines for the Diagnosis and Treatment of Integrated Traditional Chinese and Western Medicine for Female Menopausal Syndrome":An Evidence-Based Traditional Chinese Medicine Practice |
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| Abstract:Objective To develop the evidence base for the "Guidelines for the Diagnosis and Treatment of Integrated Traditional Chinese and Western Medicine for Female Menopausal Syndrome" (hereafter referred to as "the guideline"),aiming to provide effective evidence to support the formulation of recommendation statements.Methods Based on Internationally recognized methods and standards for evidence-based guideline development,the PICO (population, intervention, comparison, outcome) framework was used to construct clinical questions.A systematic literature search was conducted across domestic and international databases to identify studies published before 30 July,2022,focusing on the treatment of menopausal syndrome with integrated Chinese and Western medicine. Studies were selected based on predefined inclusion and exclusion criteria.Data extraction and synthesis were performed using ReviewManager 5.3software, and the quality of evidence was assessed employing the GRADE (Grading of Recommendations,Assessment,Development and Evaluation) methodology.Results A total of 143322 articles were retrieved,with 92studies ultimately included.These studies encompassed treatment interventions such as classical formulas,Chinese patent medicines,and distinctive therapies.The evidence from these studies was synthesized and graded,resulting in an overview of evidence pertinent to both foundational and clinical questions.ConclusionThe construction process of the evidence body in this guideline is an exploratory practice of evidence-based traditional Chinese medicine.This article reviews the important steps involved, with a view to providing a reference for the development/revision of clinical practice guidelines for traditional Chinese medicine. |
| keywords:Evidence-based medicine Female climacteric syndrome Integration of traditional and western medicine Guidelines |
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