| 神经反馈对儿童及青少年孤独症疗效的Meta分析 |
| 投稿时间：2025-02-19 修订日期：2025-03-15 点此下载全文 |
| 引用本文：王丙森,李玲,林建海,高东平.神经反馈对儿童及青少年孤独症疗效的Meta分析[J].医学研究杂志,2025,54(6):143-148 |
| DOI：
10.11969/j.issn.1673-548X.2025.06.026 |
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| 基金项目:中国妇幼健康研究会立项项目(2023CAMCHS05) |
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| 中文摘要:目的 系统评价神经反馈干预治疗儿童及青少年孤独症患者的有效性。方法 系统检索PubMed、Web of Science、Cochrane Library、ClinicalTrials.gov和中国生物医学文献数据库(China Biology Medicine, CBM),纳入使用神经反馈干预治疗儿童及青少年孤独症谱系障碍患者的随机对照试验(randomized controlled trial,RCT),检索时间为自建库至2024年12月5日,提取数据并使用 Revman 5.4.1进行Meta分析。结果 共纳入8项研究,共计381例患者。Meta分析结果显示,神经反馈组的各量表得分均低于对照组(MD=7.49,95% CI:5.33~9.65,P＜0.001)；神经反馈组的theta波功率也多有下降(OR=18.14,95% CI:7.32~44.96,P＜0.001)。结论 与安慰剂干预和常规治疗(如临床咨询或仅使用单一的干预模式)比较,神经反馈在提升孤独症儿童及青少年患者的社交能力、认知水平及情绪调节方面展现出显著的优势。 |
| 中文关键词:神经反馈 孤独症谱系障碍 Meta分析 |
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| Efficacy of Neurofeedback in Children and Adolescents with Autism:A Meta-analysis. |
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| Abstract:Objective To evaluate the efficacy of neurofeedback intervention in the treatment of children and adolescents with autism.Methods Systematically searched PubMed, Web of Science, Cochrane Library, ClinicalTrials.gov and SinoMed for randomized controlled trials using neurofeedback to treat children and adolescents with autism spectrum disorder.The search covered studies from database inception to 5th December,2024. Data were extracted and analyzed by using RevMan 5.4.1.Results A total of 8 studies were included, comprising 381 patients. The results of Meta-analysis showed that neurofeedback group had significantly lower scores on various scales compared to those inthe control group (MD=7.49,95% CI:5.33-9.65, P<0.001). Additionally, theta wave power in the neurofeedback group was notably reduced (OR=18.14,95% CI:7.32-44.96, P<0.001).Conclusion Compared to placebo interventions and conventional treatments (such as clinical counseling or one intervention models), neurofeedback demonstrates significant advantages in improving social skills, cognitive functioning, and emotional regulation in children and adolescents with autism. |
| keywords:Neurofeedback Autism spectrum disorder Meta- analysis |
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