| 不同衰弱状态下认知障碍患者的步态特征研究 |
| 投稿时间：2025-04-23 修订日期：2025-05-24 点此下载全文 |
| 引用本文：程珊珊,乔通富,孙万飞,王月菊.不同衰弱状态下认知障碍患者的步态特征研究[J].医学研究杂志,2025,54(10):84-88 |
| DOI：
10.11969/j.issn.1673-548X.2025.10.015 |
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| 基金项目:江苏省老年健康科研项目(LKZ2024008) |
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| 中文摘要:目的 分析认知障碍患者在不同衰弱状态下的步态特征,并探索能够有效区分其不同衰弱状态的敏感步态参数,为认知障碍患者的衰弱评估及干预提供参考。方法 采用回顾性研究方法,纳入2022年10月～2023年11月就诊于苏州大学附属第一医院记忆障碍门诊收治的116例认知障碍患者,采用美国Mobility LabTM APDM Opal型可穿戴设备采集步态参数,对一般临床资料和步态评估结果进行分析。结果 116例认知障碍患者中,衰弱期24例,衰弱前期67例,非衰弱期25例。多因素Logistic回归分析结果显示,步速、步幅、双支撑相和摆动相与认知障碍患者的衰弱状态显著相关,受试者工作特征(receiver operating characteristic,ROC)曲线分析结果显示,步速、步幅、双支撑相和摆动相对认知障碍患者的衰弱状态有较高的预测价值。结论 与不伴衰弱状态的认知障碍患者比较,合并衰弱状态的认知障碍患者步态障碍更显著,其中,衰弱前期组主要表现为步速减慢,步幅缩短,而衰弱组除了速度减慢、步幅缩短之外,还表现出双支撑相延长,摆动相缩短。步速、步幅、双支撑相和摆动相是识别认知障碍患者不同衰弱状态的敏感指标。 |
| 中文关键词:认知障碍 步态 衰弱 衰弱前期 |
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| Study on Gait Characteristics of Patients with Cognitive Impairment in Different Frailty States. |
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| Abstract:Objective To analyze the gait characteristics of patients with cognitive impairment in three different frailty states, and explore sensitive gait parameters that can effectively distinguish between their different frailty states, providing a reference for the assessment and intervention of frailty in patients with cognitive impairment. Methods A retrospective study was conducted. 116 patients with cognitive impairment who visited the Memory Impairment Clinic of the First Affiliated Hospital of Soochow University from October 2022 to November 2023 were included. Gait parameters were collected using the Mobility LabTM APDM Opal wearable system from the United States, and general clinical data and gait assessment results were analyzed. Results Among the 116 patients with cognitive impairment, 24 patients were in the frailty phase, 67 patients were in the pre-frailty phase, and 25 patients were in the non-frailty phase. Multivariate logistic regression analysis showed that walk velocity, stride length, double stance phase, and swing phase were significantly correlated with the frailty states of patients with cognitive impairment. Receiver operating characteristic (ROC) curve analysis showed that walk velocity, stride length, double stance phase, and swing had high predictive value for the frailty states of patients with cognitive impairment. Conclusion Compared with patients with cognitive impairment with non-frailty, patients with cognitive impairment and frailty had more significant gait disorders. Among them, the pre-frailty group mainly presented with reduced walk velocity and shortened stride length, while the frailty group, in addition to the reduced walk velocity and shortened stride length, also showed prolonged double stance phase and shortened swing phase. Walk velocity, stride length, double stance phase and swing phase are sensitive indicators for identifying different frailty states in patients with cognitive impairment. |
| keywords:Cognitive impairment Gait Frailty Pre-frailty |
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