| 重症手足口病危险因素及临床特点分析 |
| 投稿时间：2010-07-31 点此下载全文 |
| 引用本文：慎强,胡爱荣,施凯舜,李红山.重症手足口病危险因素及临床特点分析[J].医学研究杂志,2011,40(2):93-95 |
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| 中文摘要:目的了解重症手足口病的危险因素及临床特点，为完善临床治疗提供科学依据。方法回顾性分析2009年4月~2010年5月在笔者医院住院的244例手足口病患儿的临床资料。分为普通型手足口病组（普通组）和重症手足口病组（重症组），比较两组患者的临床特点，通过多因素分析筛选出重症手足口病的危险因素。 结果244例患儿中，重症手足口病58例，发生率23.7％；多因素分析显示：年龄<3岁、意识障碍、抽搐、精神差、颈抵抗、神经反射异常、体温39℃及以上>3天、外周血白细胞>12×109／L以及血糖>9mmol／L是重症手足口病的危险因素（P<0.05）。年龄、精神差、神经反射异常、体温39℃>3天以及血糖>9mmol／L等5项指标是手足口病重症化的独立性相关因素，具有早期预警作用。 结论对于年龄<3岁且有精神、神经系统症状的高热手足口病患儿需重视其病情，及早发现及正确治疗干预对提高治愈率尤为重要。 |
| 中文关键词:手足口病 重症 危险因素 临床特点 |
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| Analysis of Risk Factors and Clinical Features in Patients with Severe Hand-foot-mouth Disease |
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| Abstract:ObjectiveThe study was conducted to analyze the risk factors and clinical features of severe hand-foot-mouth disease,thus to provide scientific bases for clinical treatments. MethodsRetrospective analysis was performed to analyze the clinical data of 244 children with hand-foot-mouth disease in our hospital from April 2009 to May 2010. Clinical characteristics were compared between two groups, and risk factors of severe hand-foot-mouth disease were analyzed by logistic regression test. ResultsAmong total 244 cases, 58 cases were severe hand-foot-mouth disease, accounted for 23.7%. Logistic regression test showed that younger than 3 years, disturbance of consciousness, twitch, poor spirit, neck resistance, abnormal neural reflex, temperature 39℃ lasted than three days, WBC>12×109/L and blood glucose> 9mmol/L were the high risk factors of hand-foot-mouth disease. Age, poor spirit, abnormal neural reflex, temperature 39℃ lasting more than three days and blood glucose>9mmol/L were independented relevant factors trending to seriousness, and played an important role in early warning. ConclusionAttention should be paid to observe hand-foot-mouth disease severe trendy of children paitents younger than 3 years with nervous system symptoms and high fever. Early detection and intervention with proper treatment were particularly important for improving cure rate. |
| keywords:Hand-foot-mouth disease Severe Risk factors Cinical features |
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