| 蜂房提取物体外抗人肝癌细胞株HepG2细胞作用的实验研究 |
| 投稿时间：2011-01-18 修订日期：2011-02-16 点此下载全文 |
| 引用本文：戴关海,杨锋,童晔玲.蜂房提取物体外抗人肝癌细胞株HepG2细胞作用的实验研究[J].医学研究杂志,2011,40(11):149-151 |
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| 中文摘要:目的观察不同蜂房提取物体外抗HepG2细胞的作用。方法用不同溶剂从蜂房中提取有效成分（A～G样品），通过3H-TdR渗入法观察各提取物体外对HepG2细胞的抑制作用，确定抑瘤效果最好的蜂房提取物。结果各蜂房提取物对HepG2细胞均有很好的抑制作用，其中蜂房醇浸石油醚提取物（F样品）与蜂房醇浸乙酸乙酯提取物（G样品）的抑制作用最明显，抑制率分别为38.6%～99.6%、21.4%～98.7%，并且具有较好的量效关系。结论蜂房提取物体外具有较强的抗肿瘤作用。 |
| 中文关键词:蜂房提取物 HepG2细胞 抗肿瘤 |
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| Effect of Extracts from Nidus Vespae on Resisting Human Hepatocarcinoma Cell Line HepG2 in vitro |
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| Abstract:ObjectiveTo observe the effect of extracts from nidus vespae on resisting human hepatocarcinoma cell line HepG2 in vitro. MethodsActivity composition （A～G sample）was extracted from nidus vespae with different solvent. Sensitivity test of 3H-TdR incorporation assay was also used to detect the effect of inhibiting HepG2 cell by extracts from nidus vespae in vitro. ResultsExtracts from nidus vespae had good inhibition to HepG2 cell, especially ethanol petroleumether layer（F sample）and ethanol ethylacetate layer（G sample）.The proliferation inhibition rates were 38.6%-99.6%,21.4%-98.7%,and also had a dose-dependent manner. ConclusionExtracts from nidus vespae had good effect on resisting tumor. |
| keywords:Extracts from nidus vespae HepG2 cell Anti-tumor |
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