| 痰、纤维支气管镜刷检和胸腔积液涂片3种细胞学检查方法在原发性肺癌诊断中的应用 |
| 投稿时间：2014-10-22 修订日期：2014-11-13 点此下载全文 |
| 引用本文：陈学敬,周立娟,张莉,董宇杰,蔡毅然,张海青.痰、纤维支气管镜刷检和胸腔积液涂片3种细胞学检查方法在原发性肺癌诊断中的应用[J].医学研究杂志,2015,44(5):131-134 |
| DOI：
10.11969/j.issn.1673-548X.2015.05.036 |
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| 中文摘要:目的 探讨痰、纤维支气管镜刷检和胸腔积液细胞学在肺癌诊断中的价值。方法 收集131例经过痰、纤维支气管镜刷检和胸腔积液涂片3种方法联合检查诊断阳性,同时经组织病理学检查证实为原发性肺癌的病例,分析这3种细胞学检查方法的阳性率和分型的符合率,评价3种方法在肺癌诊断中的价值。结果 痰涂片阳性41例,阳性率31.3%;纤支镜刷检涂片阳性101例,阳性率77.1%;胸腔积液涂片阳性65例,阳性率49.6%。纤维支气管镜刷检在中心型肺癌中阳性率高(P<0.05),胸腔积液涂片在周围型肺癌中阳性率高(P<0.05)。与组织病理学分型符合率痰涂片85.4%,纤维支气管镜刷检涂片77.2%,胸腔积液涂片84.6%。结论 纤维支气管镜刷检涂片阳性率高,3种方法联合应用不仅能提高阳性检出率,也能提高分型符合率。 |
| 中文关键词:痰 纤维支气管镜刷检 胸腔积液 肺癌 |
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| Application Value of Smear Production for Sputum, Bronchial Brushing and Pleural Effusion in the Diagnosis of Primary Lung Cancer |
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| Abstract:Objective To evaluate the role of sputum, bronchial brushing and pleural effusion smears in the cytological diagnosis of lung cancer. Methods 131 patients with lung cancer were retrospectively analyzed. Sputum, bronchial brushing and pleural effusion smears were performed in all patients. The positive rate and the consistence rate of these three cytological examinations in cytological classification were analyzed. Results The positive rate in sputum, bronchial brushing and pleural effusion smears was 31.3%, 77.1% and 49.6%, respectively. The positive rate by bronchial brushing in patients was higher in central lung cancer(P<0.05),and also higher in peripheral lung cancer by pleural effusion smears(P<0.05). The consistent rate with histopathology was 85.4% in sputum smears, 77.2% in bronchial brushing smears and 84.6% in pleural effusion smears, respectively. Conclusion Bronchial brushing shows a high sensitivity in the diagnosis of lung cancer. Joint application of the three methods can not only improve the positive rate, but also improve accuracy in pathological diagnosis. |
| keywords:Sputum Bronchial brushing Pleural effusion Lung cancer |
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