纤维支气管镜肺泡灌洗治疗小儿难治性肺炎的效果评价
投稿时间:2014-12-19  修订日期:2015-01-23  点此下载全文
引用本文:丛珊,白东,张艳芹,苑修太.纤维支气管镜肺泡灌洗治疗小儿难治性肺炎的效果评价[J].医学研究杂志,2015,44(9):131-134
DOI: 10.11969/j.issn.1673-548X.2015.09.037
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作者单位E-mail
丛珊 272011 山东省济宁市第一人民医院儿科 congshan_1983@126.com 
白东 272011 山东省济宁市第一人民医院儿科  
张艳芹 272011 山东省济宁市第一人民医院儿科  
苑修太 272011 山东省济宁市第一人民医院儿科  
中文摘要:目的 探讨纤维支气管镜肺泡灌洗治疗小儿难治性肺炎的效果。 方法 90例确诊为难治性肺炎的住院患儿,分为治疗组和对照组各45例。对照组患儿给予常规祛痰、抗感染、吸氧治疗,治疗组患儿在常规治疗的基础上再加纤维支气管镜灌洗治疗,比较治疗组痰液和肺泡灌洗液细菌培养结果以及两组患儿的治疗效果。 结果 治疗组经纤维支气管镜检查多数为支气管内膜炎,占68.89%(31/45)。肺泡灌洗液细菌培养阳性率为57.78%,痰液细菌培养阳性率为22.22%,两种标本的阳性检出率差异有统计学意义(P<0.05)。治疗组有效率为86.67%,对照组有效率为53.33%,差异有统计学意义(P<0.05)。治疗组白细胞计数及中性粒细胞百分比降低幅度大于对照组(P <0.05),治疗组的住院天数及后遗症的发生率均低于对照组(P<0.05)。纤维支气管镜肺泡灌洗治疗过程中,未出现严重的并发症。 结论 纤维支气管镜肺泡灌洗治疗小儿难治性肺炎安全、有效,值得临床推广。
中文关键词:难治性肺炎  纤维支气管镜  肺泡灌洗  效果评价
 
Evaluation of Bronchoalveolar Lavage by Bronchofibroscope in the Treatment of Pediatric Patients with Refractory Pneumonia
Abstract:Objective To investigate the clinical effect of bronchoalveolar lavage by bronchofibroscope in the treatment of refractory pneumonia in children. Methods Ninety patients with refractory pneumonia were divided into two groups with 45 cases in each group. Patients in the control group were treated with conventional anti-infection, expectorant and oxygen therapy, while patients in the treatment group were treated with bronchoalveolar lavage by bronchofibroscope on the basis of conventional therapy. The bacterial culture results of the sputum and bronchoalveolar lavage fluid in the treatment group and the treatment effect of the two groups were compared. Results Endobronchial inflammation was most reason in the treatment group by bronchofibroscope, accounting for 68.89% (31/45).The positive rate of bacterial culture of bronchoalveolar lavage fluid was 57.78%, higher than that in the sputum 22.22%. The difference of two specimens was statistically significant (P<0.05). The total effective rate of treatment group was86.67%, higher than that in the control group 53.33%; the difference was statistically significant (P<0.05). The decrease of white blood cells count and percentage of neutrophils in treatment group were both more than those in control group (P<0.05). The hospital stays and the incidence of squeals of the treatment group were both less than those in control group (P<0.05). No serious complications were found in the patients who were treated by bronchoalveolar lavage. Conclusion Bronchoalveolar lavage by bronchofibroscope in the treatment of pediatric patients with refractory pneumonia is effective and safe, so it is worthy of clinical promotion and application.
keywords:Refractory pneumonia  Bronchofibroscope  Bronchoalveolar lavage  Evaluation
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