| 白介素17水平与不稳定型心绞痛严重程度相关性研究 |
| 投稿时间：2016-05-09 修订日期：2016-05-09 点此下载全文 |
| 引用本文：孙超君,唐其柱,魏捷,刘文卫,江华.白介素17水平与不稳定型心绞痛严重程度相关性研究[J].医学研究杂志,2016,45(12):116-118 |
| DOI：
10.11969/j.issn.1673-548X.2016.12.031 |
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| 中文摘要:目的 探讨白介素17水平与不稳定型心绞痛严重程度之间的相关性。方法 纳入160例不稳定型心绞痛患者，根据Braunwald分级将患者分为3组：A组为Braunwald分级Ⅰ级；B组为Braunwald分级Ⅱ级；C组Braunwald分级Ⅲ级。抽取患者入院后第2天清晨空腹时静脉血，检测其血清中白介素17（interleukin-17，IL-17）的浓度。结果 Braunwald分级越高，血清中IL-17浓度越高（P<0.05）。经多重线性回归分析，患者年龄、性别、吸烟史、高血压病病史、糖尿病病史及高脂血症病史均未显示出与IL-17之间存在相关性。结论 IL-17水平与不稳定型心绞痛严重度之间呈正相关，是预测不稳定型心绞痛严重程度的独立因子。 |
| 中文关键词:白介素17 不稳定型心绞痛 Braunwald分级 |
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| Study on Relationship between the Level of Interleukin-17 and the Severity of Unstable Angina |
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| Abstract:Objective To investigate the correlation between IL-17 levels correlated with the severity of unstable angina.Methods The study included 160 cases of unstable angina patients. According to Braunwald classification, patients were divided into three groups, A group Braunwald classification grade Ⅰ, B group Braunwald classification grade Ⅱ, C group Braunwald classification grade Ⅲ. After admission in the next morning,we extracted the fasting venous blood and detected the concentration of serum Interleukin-17.Results Braunwald classification, the higher the concentration of serum IL-17 (P<0.05). By multiple linear regression analysis, age, sex, smoking history, history of hypertension, history of diabetes and hyperlipidemia did not show a correlation with IL-17.Conclusion IL-17 levels were positively correlated with the level of severity of unstable angina.It was an independent factor to predict the severity of unstable angina. |
| keywords:Interleukin-17 Unstable angina pectoris Braunwald classification |
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