我国男性HPV流行病学特征的描述性评价
投稿时间:2017-09-04  修订日期:2017-10-06  点此下载全文
引用本文:靳大川,武淑芳,郭师,杨亚琦,李聪,王同单.我国男性HPV流行病学特征的描述性评价[J].医学研究杂志,2018,47(6):104-108
DOI: 10.11969/j.issn.1673-548X.2018.06.024
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作者单位E-mail
靳大川 450015 郑州, 河南省传染病医院国际医疗部 1452359342@qq.com 
武淑芳 450015 郑州, 河南省传染病医院国际医疗部  
郭师 450015 郑州, 河南省传染病医院国际医疗部  
杨亚琦 450015 郑州, 河南省传染病医院国际医疗部  
李聪 450015 郑州, 河南省传染病医院国际医疗部  
王同单 450015 郑州, 河南省传染病医院国际医疗部  
中文摘要:目的 分析评价我国男性普通人群人乳头瘤病毒(HPV)感染的流行学特征。方法 检索中国期刊全文数据库(CNKI)、重庆维普(VIP)、万方科技期刊全文数据库、Pubmed、Embase、OVID中关于我国男性普通人群HPV感染流行病学研究文献。采用Excel软件对提取的数据进行列表和综合分析。结果 共纳入相关研究文献5篇。综合分析显示,我国男性总的HPV感染率为8.00%~16.90%,其中高危HPV(HR-HPV)的感染率为5.50%~9.40%。与同一地区的女性人群相比,新疆墨玉县和广西林州的男性HPV感染率低于女性,而河南安阳男性的HPV感染率则高于女性。新疆和河南最常见的HR-HPV亚型均为HPV16亚型,而广西男性最常见的前3种HPV亚型依次为HPV58、52、39。新疆和河南男性的HPV多重感染率分别为1.00%和1.43%,均为当地女性HPV多重感染率的1倍以上。结论 国人男性HPV感染率低于西方国家,并存在较大的地区性差异,同一地区男性和女性常见的HR-HPV亚型分布基本一致。但是纳入的研究有限,且多为农村居民,缺乏纵向研究和对相关影响因素的研究数据,需要后续进行更全面、系统的研究。
中文关键词:人乳头瘤病毒  男性  流行病学
 
Epidemiological Feature of Human Papillomavirus in Chinese Male Population: A Descriptive Study
Abstract:Objective To study the epidemiological feature of human papillomavirus (HPV) infection in Chinese male regular population. Methods The database of Chinese National Knowledge Infrastructure (CNKI), Chongqing Weipu (VIP), Wanfang, Pubmed, Embase and OVID database were retrieved with computer for collecting studies about the epidemiology of HPV infection in Chinese male regular population. All extracted data were tabled and comprehensively evaluated with Excel software. Results A total of five studies were retrieved. The analysis showed the prevalence of HPV infection in Chinese male regular population is 8.00%-16.90% and the prevalence of HR-HPV infection is 5.50%-9.40%. Compared with that of female population from the same area, male have higher prevalence in Moyu county in Xinjiang and Linzhou county in Guangxi. However, male in Anyang county in Henan have lower prevalence compared with female. The most common HR-HPV subtype in both Xinjiang and Henan is HPV16, but in Guangxi, the three most common subtypes are HPV 58,52 and 39. The prevalence for multiple HPV subtype infection in Xinjiang and Henan are 1.00% and 1.43% respectively, which are twice the prevalence in female population. Conclusion The prevalence of HPV infection in Chinese male population is much lower than that in western countries. However, there are geographic variance in that of Chinese male population. The distribution of HPV subtypes is basically consistent in male and female population. But the studies recruited are limited and most population is from countryside. Also longitudinal research and studies for relevant influence factors were not carried out. Further more comprehensive and systematic studies are important in the future.
keywords:Human papillomavirus  Male  Epidemiology
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