| 脑卒中患者脑萎缩的相关危险因素分析 |
| 投稿时间：2018-01-02 修订日期：2018-03-18 点此下载全文 |
| 引用本文：毛蕾,王博,刘团结,沈滔,徐玉萍.脑卒中患者脑萎缩的相关危险因素分析[J].医学研究杂志,2018,47(12):91-95 |
| DOI：
10.11969/j.issn.1673-548X.2018.12.022 |
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| 基金项目:上海市科学技术委员会基金资助项目（16411972900） |
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| 中文摘要:目的 探索影响脑卒中后脑萎缩的独立危险因素。方法 选取合并有脑卒中史的脑萎缩患者150例作为观察组，同期182例脑卒中患者对照组。收集患者的一般情况及既往史，用颈动脉超声对患者进行双侧颈总动脉检测，利用磁共振成像进行颈内动脉狭窄检测。利用Logistic多因素回归分析脑卒中后脑萎缩的独立影响因素。利用ROC曲线分析脑卒中后脑萎缩的潜在评估指标。结果 Logistic回归分析显示，心肌梗死或心绞痛，心房颤动、大脑中动脉平均血流速度、颈内动脉颅内段平均血流速度、糖尿病对脑卒中后脑萎缩发生的独立危险因素（P<0.05），ROC曲线分析发现，大脑中动脉平均血流速度联合颈内动脉颅内段平均血流速度评估脑卒中后脑萎缩的准确性较高（AUC=0.864）。结论 大脑中动脉和颈内动脉颅内段检测可预防脑卒中后脑萎缩，对于有相关病史的脑卒中患者及早进行脑萎缩预防有重要临床意义。 |
| 中文关键词:脑卒中 脑萎缩 影响因素 |
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| Analysis of Risk Factors Related to Brain Atrophy in Stroke Patients |
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| Abstract:Objective To explore the independent risk factors of brain atrophy after stroking. Methods One hundred fifty stroke patients with atrophy were involved as observation group and 182 patients with stroke were involved with control group. The general condition and history of patients were collected. The carotid artery was examined by ultrasonography and the internal carotid artery was detected by magnetic resonance imaging. The relevant indicators of the patient's age and other index were analyzed by SPSS19.0 and the impact factors of brain atrophy were select into Logistic regression analysis. The ROC curve was used to assess the value of the relevant factors in the occurrence of brain atrophy in stroke patients. Results Logistic regression analysis showed that myocardial infarction or angina pectoris, atrial fibrillation, middle cerebral artery mean blood flow velocity, internal carotid artery intracranial mean blood flow velocity, diabetes were the independent risk factors of brain atrophy after stroking (P<0.05). The ROC curve analysis showed that the accuracy of the evaluation of brain atrophy after stroking by middle cerebral artery mean blood flow velocity combined with internal carotid artery intracranial mean blood flow velocity was highest (AUC=0.864). Conclusion In the brain atrophy of stroke patients, intracranial stenosis of middle cerebral artery and internal carotid artery has a great influence. For the stroke patients with related history, early prevention for brain atrophy has important clinical significance. |
| keywords:Stroke Brain atrophy Influencing factors |
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